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.github/profile/README.md
Four-panel comic of my career path. Panel 1: an elephant labeled 'Statistics' stands next to a small snake labeled 'Computer Science'. Panel 2: the snake says 'We will work together' and wraps around the elephant's tail. Panel 3: the elephant pleads 'Please teach me statistics' as the snake swallows it. Panel 4: the snake has grown into a long-necked dinosaur that proudly declares 'Now I'm DATA SCIENTIST', while a meteor labeled 'AI' heads straight for it.

Hello! 👋

I'm Florian, and I work on AI for biomedical images 🧠. My path here was anything but straight: I studied psychology and sociology in Munich, worked as a freelance data scientist, and then drifted into computer science for my PhD at TUM. I never fully left psychology behind, and it still shapes how I think about experts and their perception.

After research positions at Helmholtz Munich and the University of Zürich, I'm now at the Hertie Institute for AI in Brain Health in Tübingen. There, our group, the Kofler Lab, builds bridges between the academic ivory tower and the clinic and biology lab: bringing expert knowledge into machine learning models, and machine learning models into expert workflows.

Concretely, we ask whether our metrics actually reflect what experts see. With psychophysics and eye-tracking, we study how experts judge quality, and we treat label noise and annotation uncertainty as a signal rather than a nuisance. From there, we build better tools: losses like blob loss, evaluation frameworks like panoptica, and the BrainLesion Suite for getting methods into practice. We also develop generative models, such as diffusion-based inpainting of healthy brain tissue, and work out how to judge synthetic images the way experts would, across MRI, CT, and microscopy.

Biomedical AI succeeds not by replacing experts, but by keeping them firmly in the loop.

Happy to chat about open science, reproducibility, or turning research into tools people actually use.

👉 Check out koflerlab on GitHub for our latest work.


🔭 Things we're building together

  • 🧪 koflerlab: our group's home, with all our lab repositories
  • 🧠 BrainLesion: a community organization building open-source tools for brain lesion image analysis
  • 🏆 BraTS Inpainting Challenge: a community benchmark we co-organize, with its own organization

All of these are collaborative efforts. Issues, pull requests, and ideas are very welcome.


📫 Connect

LinkedIn Google Scholar Hertie AI X Instagram

📰 News about our work: I post updates on LinkedIn, and new papers land on Google Scholar.

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  1. BraTS-Toolkit BraTS-Toolkit Public

    Code to preprocess, segment, and fuse glioma MRI scans based on the BraTS Toolkit manuscript.

    Python 106 14

  2. blob_loss blob_loss Public

    blob loss example implementation

    Python 37 2

  3. BrainLesion/panoptica BrainLesion/panoptica Public

    panoptica -- instance-wise evaluation of 3D semantic and instance segmentation maps

    Python 34 11

  4. BrainLesion/preprocessing BrainLesion/preprocessing Public

    preprocessing tools for multi-modal 3D brain imaging

    C 39 11

  5. BraTS-inpainting/2025_challenge BraTS-inpainting/2025_challenge Public archive

    BraTS 2025 Inpainting Challenge (Local Synthesis Challenge)

    Jupyter Notebook 7 1

  6. BrainLesion/BraTS BrainLesion/BraTS Public

    Providing top-performing algorithms from the Brain Tumor Segmentation (BraTS) challenges.

    Python 87 19