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Eric Nawrocki edited this page Sep 16, 2026 · 74 revisions

VADR wiki

VADR (Viral Annotation DefineR) is a tool for validation and annotation of virus sequence submissions to GenBank.

Use the sidebar to navigate. This wiki covers:

  • Annotation guides — how to run VADR for SARS-CoV-2, influenza, mpox virus, RSV and Zika virus.
  • GenBank processing versions — which VADR version, models and command-line options GenBank has used, and when, for the viruses it processes automatically.
  • Models and reference — available model files and download instructions, Rfam-based structural annotation of a viral genome sequence, and development notes.

Questions, comments or feature requests? Send a mail to eric.nawrocki@nih.gov.

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