diff --git a/Formula/c/ctk.rb b/Formula/c/ctk.rb
new file mode 100644
index 0000000000000..1ba889646a09a
--- /dev/null
+++ b/Formula/c/ctk.rb
@@ -0,0 +1,49 @@
+class Ctk < Formula
+  desc "Support code for medical imaging, surgical navigation, and related purposes"
+  homepage "https://github.com/commontk/CTK"
+
+  url "https://github.com/commontk/CTK/archive/refs/tags/2026.08.06.tar.gz"
+  sha256 "e2d8376b2b1644ec7112d4779549cf96cb486e671f1cb6f00ac0e3f27f1379ae"
+  license "Apache-2.0"
+  head "https://github.com/commontk/CTK.git", branch: "master"
+
+  depends_on "cmake" => :build
+  depends_on "pkgconf" => :test
+  depends_on "itk"
+  depends_on "qt5compat"
+  depends_on "qtbase"
+  depends_on "qtmultimedia"
+  depends_on "qtscxml"
+  depends_on "qtsvg"
+  depends_on "qttools"
+  depends_on "qtwebengine"
+  depends_on "vtk"
+
+  def install
+    args = %w[
+      -DCTK_QT_VERSION=6
+      -DCTK_SUPERBUILD=OFF
+    ]
+    system "cmake", "-S", ".", "-B", "builddir", *args, *std_cmake_args
+    system "cmake", "--build", "builddir"
+    system "cmake", "--install", "builddir"
+  end
+
+  test do
+    (testpath/"test.cpp").write <<~CPP
+      #include <ctkLogger.h>
+      int main() {
+          ctkLogger logger("org.commontk.test");
+          logger.info("OK");
+          return 0;
+      }
+    CPP
+    flags = shell_output("pkgconf --cflags --libs Qt6Core").chomp.split
+    system ENV.cxx, "-std=c++17", "test.cpp",
+           "-I#{include}/ctk-0.1",
+           "-L#{lib}/ctk-0.1", "-lCTKCore",
+           "-o", "test", *flags
+    ENV["LD_LIBRARY_PATH"] = "#{lib}/ctk-0.1" if OS.linux?
+    system "./test"
+  end
+end